Silk Road; encountered two oceans – Pacific Ocean and Atlantic Ocean-, two continents – Asia and Europe-, many cultures, civilizations, religions, philosophical lives and life styles, commercial benefits of all people need, and also nations for thousands years, and it has a very distinctive and effective feature on being the greatest trade road of the world. As well as connecting thousands of settlements, Turkish Homelands, and near east countries each other, with its more than ten thousands kilometers length Silk Road that is the longest highway of the old World, made these countries’ export and import easy, it had an important role in the trades of the region countries as well as the World trade. Having such a great importance, the Silk Road passed through Turkish homelands from the oldest time to middle age. The nationalities and the countries to dominate the Silk Road continued their dominance struggles on these Turkish homelands. Turkish Homelands were somehow are similar to the Silk Road. The dominant of these Turkish Homelands were also the dominant of the Silk Road. In regard to this topic that we handled The Silk Road Dominance and Turk- Arab struggles on the Turkish Homelands are examined.