Though it has been well acknowledged that Uzbekistan has experienced improvement in economic and human development over the last three decades, this paper studies the impact of ethnicity, religion and region on discernment of socio-economic and socio-cultural change. Footed on an outcome of the study in Uzbekistan in 201011, we discovered that despite of background features, a bulk of people tales socio-economic advancement, more ethnic integration and less favouritism. Even though traditio nally excluded ethnic and religious groups are somewhat less likely to report social improvements than more privileged groups, two models of socio-economic and socio-cultural change show that such group differences disappear when controlling for socio-economic and other background characteristics. The survey data from our study unequivocally show that there are considerable differ¬ences across ethnic, regional and religious groups on indicators of socio-economic status. This applies to literacy, educational levels, income and consumption levels, as well as to amenities and con¬sumer goods. Social interaction between different ethnic, religious and regional groups is constricted by deeply entrenched cul¬tural norms that prohibit direct contact between them. These groups are not confined to one geographical area but are scattered all over the country. In the present research paper the relationship between perceptions of social change and the impact of ethnicity, religion and region has been attempted to explore with well designed methodology. This article is concerned with people’s perceptions of the extent of socio-economic and socio-cultural change that has taken place in Uzbekistan and how these perceptions vary across individual, household and community variables. In particular the focus is on the perspicacity of social change and the effects of ethnicity, religion and region, which are features that predominate in the discussion of inclusion and exclu¬sion in Uzbekistan.